Medications and Skin Disease - Q to Z

quaalude

fixed drug eruption

quinacrine

alopecia, eczema, exfoliative dermatitis, ochronosis, pigmentation (yellow)

quinidine

eczema, erythroderma, exanthematous eruption, exfoliative dermatitis, fixed drug eruption, Henoch-Schönlein purpura, LE, lichenoid, livedo reticularis, petechiae, phototoxic drug eruption, porphyria cutanea tarda, pruritus, psoriasis, purpuric eruption, pustular eruption, rash, thrombocytopenic purpura, urticaria, vasculitis (leukocytoclastic)

quinine

acneiform eruption, cutaneous small vessel vasculitis, fixed drug eruption, Henoch-Schönlein purpura, histamine release, lichenoid, livedo reticularis, petechiae, porphyria cutanea tarda, purpura, TEN, vasculitis (leukocytoclastic)

radiocontrast media

histamine release

reserpine

LE, rosacea

resorcinol

eczema, ochronosis

retinoids

alopecia, ichthyosiform, mucositis

rifampin

erythema multiforme, exfoliative dermatitis, flushing, pemphigus foliaceus, pemphigus vulgaris, porphyria cutanea tarda, TEN

salazopyrin

erythema multiforme

salicylanilides

persistent light reaction

salicylates

bullous eruption, erythema annulare centrifugum, erythema multiforme, erythema nodosum, fixed drug eruption, urticaria, vesiculobullous

scopolamine

histamine release

sedatives

purpura, purpura pigmentosa chronica, xerostomia

serum

vasculitis (leukocytoclastic)

silver

hyperpigmentation (dermal)

somatostatin

linear IgA d.

sotalol

vasculitis (leukocytoclastic)

spironolactone

hypertrichosis

steroids

pseudolymphoma

streptokinase

vasculitis (leukocytoclastic)

streptomycin

cutaneous small vessel vasculitis, eczema, EM, exanthematous eruption, exfoliative dermatitis, hypertrichosis, LE, lichenoid, rash, TEN, urticaria, vasculitis (leukocytoclastic)

sulfa

nail color change (blue), pemphigoid, serum sickness-like vasculitis

sulfadizine

exfoliative dermatitis

sulfanilamide

phototoxic drug eruption

sulfapyridine

pellagra-like

sulfasalazine

bullous pemphigoid, erythroderma

sulfathiazole

panniculitis

sulfonamides

cutaneous small vessel vasculitis, eczema, erythema multiforme, erythema nodosum, erythroderma, exanthematous eruption, exfoliative dermatitis, fixed drug eruption, nail changes, photoallergic drug reaction, photosensitivity, phototoxic drug eruption, pruritus, purpuric eruption, rash, serum sickness-like, SLE, TEN, urticaria, vasculitis (leukocytoclastic), vesiculobullous

sulfones

erythema nodosum

sulfonylureas

lichenoid eruption, erythema multiforme, erythema nodosum, exfoliative dermatitis, lichenoid, photoallergic drug reaction, photosensitivity, phototoxic drug eruption, porphyria cutanea tarda, SCLE

sulindac

chilblains-like erythema, fixed drug eruption

suramin

acral erythema, erythema multiforme, flushing, papules (keratotic), pruritus, TEN, UV recall

tacrolimus

hypertrichosis

tamoxifen

cutaneous small vessel vasculitis, dermatomyositis-like, flushing, hair color change, hirsutism, vasculitis (leukocytoclastic)

tar

acneiform eruption, folliculitis, nail color change (yellow)

tartrazine

purpura

tegafur

acral erythema, dermatomyositis-like, hyperpigmentation, hyperpigmentation (mucosal), LE, lichenoid, phototoxic drug eruption, stomatitis

teniposide

alopecia, flushing, urticaria

terbutaline

exfoliative dermatitis

testosterone

alopecia, hypertrichosis, pruritus

tetracycline

black hairy tongue, candidiasis, EM, erythema nodosum, exanthematous eruption, fixed drug eruption, lichenoid, nail color change (yellow), onycholysis, photosensitivity, phototoxic drug eruption, PCT, pseudoporphyria, SLE, splinter hemorrhage, TEN, urticaria, vasculitis (leukocytoclastic)

thallium

alopecia, anagen effluvium

theophylline

rosacea

thiamin

histamine release

thiazides

cutaneous small vessel vasculitis, eczema, erythema nodosum, exanthematous eruption, exfoliative dermatitis, lichenoid, onycholysis, photoallergic drug reaction, photosensitivity, phototoxic drug eruption, rash (morbilliform), purpura, SCLE, serum sickness-like vasculitis, thrombocytopenic purpura, vasculitis (leukocytoclastic), vesiculobullous

thiobendazole

TEN

thioguanine

stomatitis

thiol derivatives

pemphigoid

thiopronine

elastosis perforans serpiginosa, pemphigus vulgaris

thioridazine

vesiculobullous

thiotepa

alopecia, hyperpigmentation, urticaria

thiouracil

alopecia, anagen effluvium, rash, SLE, vasculitis

thyroid hormones

hypertrichosis

thyrotropin-releasing hormone

flushing

timolol

erythroderma

tobacco

Raynaud’s d.

tolbutamide

phototoxic drug eruption, pruritus

tolmetin

fixed drug eruption

tomudex

stomatitis

topotecan

alopecia, stomatitis

trazodone

exanthematous eruption, exfoliative dermatitis, urticaria

triazinate

acanthosis nigricans

tricyclic antidepressants

xerostomia

trimethadione

acneiform eruption, alopecia, erythema multiforme, SLE

trimethoprim

erythema multiforme, urticaria

trimethoprim/sulfadoxine

TEN

trimethoprim-sulfamethoxasole

erythema multiforme, erythroderma, exanthematous eruption, exfoliative dermatitis, fixed drug eruption, leukocytoclastic vasculitis, linear IgA d., rash, TEN, urticaria

trimetrexate

flushing, urticaria

triparanol

alopecia, ichthyosiform

tripelennamine

pityriasiform

tryptophan

dermatomyositis-like, eosinophilic fasciitis (contaminated), sclerosis

vaccines

erythema nodosum, vasculitis (influenza)

valproic acid

alopecia, scleroderma-like, TEN

vancomycin

exfoliative dermatitis, histamine release, linear IgA d., “red man” s., TEN, vasculitis (leukocytoclastic)

vasodilators

rosacea

verapamil

erythermalgia, flushing, gingival hyperplasia

vigabatrin

linear IgA d.

vinblastine

acneiform eruption, alopecia, photoallergic drug reaction, photosensitivity,  phototoxic drug eruption, stomatitis

vincristine

acral erythema, alopecia, Raynaud’s d., stomatitis, urticaria

vindesine

alopecia

vinorelbine

alopecia, hyperpigmentation

vinyl chloride

Raynaud’s d., scleroderma-like

vitamin A

alopecia

vitamin B complex

pruritus

vitamin B12 (cyanocobalamin)

acneiform eruption

vitamin K (IM)

sclerosis

vitamins

vasculitis (leukocytoclastic)

zidovudine

exfoliative dermatitis, longitudinal pigmented nail streaks, hyperpigmentation (nail), hyperpigmentation (linear)

zinostatin

urticaria