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Therapy
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Therapy (unusual and regimes)
alpha methyldopa | Raynaud’s s. |
aluminum chloride | Hailey-Hailey d. |
aminocaproic acid | angioedema |
amphotericin B | mucocutaneous leishmaniasis |
anthralin | alopecia areata |
antidepressants | chronic urticaria (doxepin), paroxysmal pruritus, pruritus vulvae |
antimalarials | dermatomyositis, hydroa vacciniforme, inflammatory morphea, PMLE, reticular erythematous mucinosis, solar urticaria, |
aspirin | atrophie blanche, Degos’ d., erythromelalgia, Kawasaki’s d., polyarteritis nodosa |
azathioprine | dermatomyositis, erythroderma, immunobullous disease, LE, leukocytoclastic vasculitis, livedo reticularis, pemphigus, persistent light reaction, PRP, PSS, pyoderma gangrenosum |
azelic acid | acne |
benzodiazepines | causalgia |
b-carotene | DLE, erythropoietic protoporphyria |
bleomycin | genital warts, keratoacanthoma |
calcium gluconate | periungual chemical burns |
cantharidin | molluscum, verrucae |
capsaicin | post-herpetic neuralgia, pruritus |
carbachol | Chediak-Higashi s. |
carmustine (BCNU) | lymphomatoid papulosis, mycosis fungoides |
charcoal | erythrocytic porphyria, pruritus of renal dialysis |
chlorambucil | mucinoses |
chloripramine | trichotillomania |
chloroquine | PCT, REM s. |
cholestyramine | biliary pruritus, circumileostomy eczema, PCT, primary biliary cirrhosis |
cimetidine | chronic mucocutaneous candidiasis, Kaposi’s sarcoma |
clindamycin | Fox-Fordyce d., rosacea, vulvovaginal LP |
clofazimine | DLE, pyoderma gangrenosum, Sweet’s s. |
clonidine | hyperhidrosis |
colchicine | amyloidosis, aphthae, Behçet’s disease, EBA, erythema nodosum, familial Mediterranean fever, idiopathic thrombocytopenic purpura, leukocytoclastic vasculitis, nodular vasculitis, palmoplantar pustular psoriasis, PG, pustular psoriasis, Sweet’s s. |
cyclophosphamide | allergic granulomatosis, dermatomyositis, erythroderma, immunobullous disease, leukocytoclastic vasculitis, mucinoses, pemphigus, polyarteritis nodosa, PSS, Wegener’s granulomatosis |
cyclosporin A | aphthous ulcers, atopic dermatitis, alopecia areata, Behçet’s disease, dermatomyositis, EBA, erosive LP, generalized granuloma annulare, GVHD, pemphigus, pompholyx, psoriasis, pustulosis palmaris et plantaris, pyoderma gangrenosum, Reiter’s s., scleroderma, urticaria/angioedema |
cyproheptadine | acanthosis nigricans, acne, carcinoid s., cold urticaria |
DMSO | lipoid proteinosis, primary amyloidosis, Raynaud’s ulceration |
dacarbazine | KS, melanoma |
danazol | acne, angioedema, idiopathic thrombocytopenic purpura, premenstrual exacerbation of SLE, urticaria |
dapsone | acropustulosis of infancy, acne conglobata, acne fulminans, actinomycosis, alopecia mucinosa, alpha 1 antitrypsin deficiency panniculitis, benign mucosal pemphigoid, brown recluse spider bites, bullous LE, bullous pemphigoid (young patients), chronic bullous disease of childhood, cicatricial pemphigoid, dermatitis herpetiformis, EED, GA, granuloma faciale, Hailey-Hailey d., Henoch-Schönlein purpura, LP/LE overlap, leishmaniasis, leprosy, leukocytoclastic vasculitis, linear IgA d., lymphomatoid papulosis, palmoplantar pustular psoriasis, pemphigus foliaceus, pemphigus vulgaris, pyoderma gangrenosum, relapsing polychondritis, SCLE, urticarial vasculitis |
dexamethasone | hirsutism |
dibutyl ester | alopecia areata |
dilantin | DEB, JEB, glucagonoma, morphea |
diltiazem | hyperhidrosis |
dinitrochlorobenzene | alopecia areata |
diphencyprone | alopecia areata |
disodium cromoglycate | mastocytosis (relief of GI, skin & CNS symptoms) |
disulfiram | nickel sensitivity |
DMSO | hereditary localized pruritus |
doxycycline | bullous pemphigoid |
epinephrine | angioedema, mastocytosis |
estrogens | hereditary hemorrhagic telangiectasia, rosacea |
etoposide | Langerhan’s cell histiocytosis |
etretinate | keratoacanthoma, LP, PRP, psoriasis, pustular psoriasis, pustulosis palmaris et plantaris |
evening primrose oil | atopic dermatitis |
finasteride | androgenetic alopecia, hirsutism |
fluoxetine | skin picking |
flutamide | hirsutism |
5-fluorouracil | actinic keratoses, basal cell epithelioma (superficial), condyloma, erythroplasia of Queyrat, KA (IL and topically), Paget’s d., verrucae |
fotemustine | melanoma |
gentamicin | protothecosis |
gold | DLE (Auranofin), pemphigus, psoriatic arthritis |
grenz ray | lichen simplex chronicus |
guanethidine | Raynaud’s d. |
hydroxychloroquine | DLE, PCT, REM s., subacute LE |
IFN-a | episodic angioedema, hypereosinophilic s. |
IFN-g | atopic dermatitis |
indomethacin | Reiter’s s. |
interferon (a & g) | basal cell epithelioma, BCC, SCC, warts (genital), vulvodynia |
isotretinoin | Darier’s disease, DLE, ichthyoses, mucinoses, PRP, psoriasis (pustular, erythrodermic) |
itraconazole | protothecosis |
ketanserin | Raynaud’s phenomenon |
ketotifen | physical urticaria |
KI | Sweet’s s., erythema nodosum, subacute nodular migratory panniculitis, granuloma annulare, nodular vasculitis, blastomycosis, zygomycosis |
levamisole | LP, SLE |
masoprocol | actinic keratoses |
melphalan | papular mucinoses, primary systemic amyloidosis |
mercury | yellow oxide of mercury for eyelash pediculosus |
metronidazole | acute necrotizing gingivitis, anaerobic infection of leg ulcers, rosacea |
methotrexate | dermatomyositis, erythroderma, Hailey-Hailey d., immunobullous disease, keloids, keratoacanthoma, lymphomatoid papulosis, multicentric histiocytosis, Norwegian scabies (crusted), PLEVA, PRP, psoriasis |
minoxidil | alopecia areata |
niacinamide | bullous pemphigoid, granuloma annulare, Hartnup d. |
nifedipine | Raynaud’s s. |
nitrogen mustard | CTCL |
OCPs | acne, hirsutism |
papaverine | atopic dermatitis |
pentoxyfylline | atrophie blanche, CNCH, leukocytoclastic vasculitis, livedo reticularis, PLEVA, Raynaud’s s. |
phlebotomy | PCT |
photopheresis | CTCL, cutaneous sclerosis, GVH d. |
pimozide | acarophobia, acne excor¾e, dermatitis artefacta, delusion of parasitosis, monosynaptic hypochondriasis, onychotillomania, orodynia, total lipodystrophy |
plasmapheresis | mucinoses, pemphigus |
podofilox | condyloma |
prazequantel | cysticercosis, schistosomiasis |
prazosin | Raynaud’s phenomenon |
prolixin | acarophobia |
propylene glycol | 2:1 mixture with water for softening calluses/corns |
psoralen + UVA PUVA | allergic contact dermatitis, alopecia areata, alopecia mucinosa, atopic dermatitis, CTCL, erythropoietic protoporphyria, granuloma annulare, Grover’s d., GVH d., hydroa vacciniforme, LP, mastocytosis, morphea, persistent light reactor, pityriasis lichenoides chronica, lymphomatoid papulosis, parapsoriasis, pityriasis lichenoides, PLEVA, PMLE, polycythemia vera, pompholyx, PRP, psoriasis, pustulosis palmaris et plantaris, scleroderma, solar urticaria, urticaria pigmentosis, vitiligo |
rePUVA | combination systemic retinoids plus PUVA for psoriasis |
retinoids | aphthae, BCC, Darier’s d., Grover’s d., hidradenitis suppurativa, KA, keratodermas, LE, psoriasis, rosacea, SC, XP |
spironolactone | acne, hirsutism |
squaric acid | alopecia areata |
sulfur | scabies (pregnant women & infants <2 months old) |
stanozolol | atrophie blanche, cryofibrinogen leg ulcers, cutaneous polyarteritis nodosa, NLD |
thalidomide | actinic prurigo, aphthous ulcers (AIDS), chronic GVH, erythema nodosum leprosum, LE, PMLE, uremic pruritus |
trimethoprim-sulfamethoxasole | chronic granulomatous d., nocardiosis |
testosterone | lichen sclerosis |
tetracycline | Vibrio infections, protothecosis |
thalidomide | aphthae, Behçet’s d., erythema nodosum leprosum, lupus profundus, prurigo nodularis, systemic nodular panniculitis (Weber-Christian) |
thiabendazole | seabather’s eruption |
UVA/UVB | atopic dermatitis, pruritus |
vinblastine | Kaposi’s sarcoma |
vitamin A | acneiform eruptions, acne, corns, Darier’s d., Grover’s d. |
vitamin C | alkaptonuria, Chediak-Higashi s., Ehlers-Danlos type VI, miliaria |
vitamin D | psoriasis, parapsoriasis |
zinc sulfate | alopecia areata |
Disease Therapy
a-1 antitrypsin deficiency panniculitis | dapsone |
acanthosis nigricans | cyproheptadine |
acarophobia | pimozide, prolixin |
acne | azelic acid, cyproterone, danazol, spironolactone, vitamin A |
acne conglobata | dapsone |
acne excoree | pimozide |
acne fulminans | dapsone |
acneiform eruptions | vitamin A |
acropustulosis of infancy | dapsone |
actinomycosis | dapsone |
acute necrotizing gingivitis | metronidazole |
alkaptonuria | vitamin C |
allergic granulomatosis | cyclophosphamide |
alopecia areata | anthralin, cyclosporine A, dibutyl ester, dinitrochlorobenzene, diphencyprone, minoxidil, squaric acid, zinc sulfate |
alopecia mucinosa | dapsone, psoralens |
amyloidosis, primary | DMSO |
angioedema | aminocaproic acid, danazol |
aphthae | colchicine, thalidomide |
atopic dermatitis | evening primrose oil, papaverine, psoralens |
atopy | cyclosporine A |
atrophie blanche | pentoxyfylline, stanozolol, aspirin |
Behçet’s d. | thalidomide |
benign mucosal pemphigoid | dapsone |
biliary pruritus | cholestyramine |
blastomycosis | KI |
brown recluse spider bite | dapsone |
bullous LE | dapsone |
bullous pemphigoid | dapsone, doxycycline, niacinamide |
causalgia | benzodiazepines |
Chediak-Higashi s. | carbachol, vitamin C |
chronic bullous disease of childhood | dapsone |
chronic granulomatous d. | trimethoprim-sulfamethoxasole |
chronic mucocutaneous candidiasis | cimetidine |
CNCH | pentoxyfylline |
cold urticaria | cyproheptadine |
corns | vitamin A |
corns/calluses | propylene glycol |
cryofibrinogen leg ulcers | stanozolol |
cutaneous polyarteritis nodosa | stanozolol |
cysticercosis | prazequantel |
Darier’s d. | dermabrasion, laser, oral retinoids, oral vitamin A |
DEB | dilantin |
Dego’s d. | aspirin |
dermatitis artefacta | pimozide |
dermatitis herpetiformis | dapsone |
dermatomyositis | antimalarials, azathioprine, cyclophosphamide, methotrexate |
DLE | beta-carotene, clofazimine, hydroxychloroquine, isotretinoin, gold |
eczema, circumileostomy | cholestyramine |
EED | dapsone |
Ehlers-Danlos type VI | vitamin C |
entomophthoromycosis | KI |
erythema nodosum | colchicine, KI |
erythema nodosum leprosum | thalidomide |
erythrocytic porphyria | charcoal |
erythroderma | azathioprine, cyclophosphamide, methotrexate |
erythromelalgia | aspirin |
familial Mediterranean fever | colchicine |
glucagonoma | dilantin |
Goeckerman regime | treatment of psoriasis; UV plus crude coal tar |
granuloma annulare | dapsone, KI, niacinamide |
granuloma annulare, generalized | cyclosporine A |
granuloma faciale | dapsone |
Grover’s d. | PUVA, retinoids (oral), steroids, vitamin A |
Hailey-Hailey d. | aluminum chloride hexahydrate 6.25%, dapsone, vitamin E, methotrexate, cyclosporin (topical) |
harlequin fetus | oral retinoids |
Hartnup d. | niacinamide |
Henoch-Schönlein purpura | dapsone |
hereditary hemorrhagic telangiectasia | estrogens |
hirsutism | dexamethasone, finasteride, flutamide, OCPs, spironolactone |
hydroa vacciniforme | antimalarials |
hyperhidrosis | clonidine, diltiazem |
idiopathic thrombocytopenic purpura | colchicine, danazol |
inflammatory morphea | antimalarials |
Ingram treatment | anthralin paste, UV & wraps; psoriasis treatment |
JEB | dilantin |
Kaposi’s sarcoma | cimetidine |
Kawasaki’s d. | aspirin |
keloids | methotrexate |
keratoacanthoma | bleomycin, etretinate, 5-fluorouracil, methotrexate |
keratoderma | biotin, salicylic acid, retinoids (oral), vitaminD3 analog, |
LE | azathioprine |
leg ulcers, anaerobic infection | metronidazole |
leishmaniasis | dapsone |
leukocytoclastic vasculitis | colchicine, pentoxyfylline |
lichen planus | levamisole |
lichen planus, lupus erythematosus overlap | dapsone |
lichen sclerosis | steroids |
lichen simplex chronicus | grenz ray |
linear IgA bullous dermatosis | dapsone |
livedo reticularis | azathioprine |
lupus profundus | thalidomide |
lymphomatoid papulosis | carmustine (BCNU), dapsone, methotrexate |
mastocytosis | psoralens |
miliaria | vitamin C |
monosynaptic hypochondriasis | pimozide |
morphea | dilantin |
mucocutaneous leishmaniasis | amphotericin B |
multicentric histiocytosis | methotrexate |
mycosis fungoides | carmustine (BCNU) |
necrobiosis lipoidica diabeticorum | stanozolol |
nickel sensitivity | disulfiram |
nocardiosis | trimethoprim-sulfamethoxasole |
nodular vasculitis | colchicine |
Norwegian scabies | methotrexate |
onychotillomania | pimozide |
orodynia | pimozide |
palmoplantar pustular psoriasis | colchicine, dapsone |
panniculitis, subacute nodular migratory | KI |
parapsoriasis | psoralens, vitamin D |
paroxysmal pruritus | amitryptiline |
PCT | phlebotomy |
pediculosis, eyelash | mercury, petrolatum |
pemphigus foliaceus | dapsone |
pemphigus vulgaris | dapsone |
periungual chemical burns | calcium gluconate |
persistent light reactor | azathioprine, psoralens |
pityriasis lichenoides chronica | psoralens |
PLEVA | methotrexate, pentoxyfylline, psoralens |
PMLE | antimalarials, psoralens |
polyarteritis nodosa | aspirin, cyclophosphamide |
polycythemia vera | psoralens |
pompholyx | psoralens (PUVA) |
premenstrual exacerbation of SLE | danazol |
primary biliary cirrhosis | cholestyramine |
protothecosis | gentamicin, itraconazole, tetracycline |
PRP | azathioprine, etretinate, methotrexate |
prurigo nodularis | thalidomide |
pruritus | antihistamines, capsaicin, diphenhydramine, doxepin cream, pramoxine HCl |
pruritus of renal dialysis | charcoal |
pruritus vulvae | amitryptiline |
pruritus, hereditary localized | DMSO |
psoriasis | cyclosporine A, vitamin D |
PSS | azathioprine, cyclophosphamide |
pustular psoriasis | colchicine, etretinate |
pyoderma gangrenosum | azathioprine, clofazimine, dapsone, mycophenolate mofetil |
Raynaud’s s. | alpha methyldopa, nifedipine |
Raynaud’s ulceration | DMSO |
relapsing polychondritis | dapsone |
reticular erythematous mucinosis | antimalarials |
rosacea | azelaic acid, clonidine, estrogens, metronidazole, retinoids, spironolactone |
schistosomiasis | prazequantel |
SCLE | dapsone |
seabather’s eruption | thiobendazole |
skin picking | fluoxetine |
SLE | levamisole |
solar urticaria | antimalarials, psoralens |
Sweet’s s | KI, colchicine, clofazimine |
systemic nodular panniculitis (Webber-Christian) | thalidomide |
total lipodystrophy | pimozide |
urticaria pigmentosis | psoralens |
urticaria, chronic | Doxepin |
urticaria, physical | ketotifen |
urticarial vasculitis | dapsone |
vasculitis, nodular | KI |
Vibrio infections | tetracycline |
Wegener’s granulomatosis | cyclophosphamide |
zygomycosis | KI |
Herbal Therapy
acne | burdock root, tea tree oil, yellow dock |
bruising | arnica, capsaicin, comfrey |
burns | aloe vera, calendula |
eczema | aloe vera, burdock, chamomile, evening primrose oil, witch hazel |
herpes | lemon balm |
onychomycosis | tea tree oil |
pruritis | capsaicin, chamomile, chickweed |
psoriasis | aloe vera, burdock root, capsaicin, milk thistle, red clover, yellow dock |
shingle pain | capsaicin |
tinea pedis | garlic, tea tree oil |
ulcers, wounds | aloe vera, arnica, calendula, comfrey, echinacea, goldenseal, tea tree oil |
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